The latest research by IBS-HICoE research group described the main role of splenic dendritic cells in destroying Infectious Bursal Disease Virus (IBDV). The study showed the differential regulation of dendritic cells in chickens inoculated with IBDV vaccine and very virulent strains. The finding of this study is currently being further studied in detail for the development of new generation vaccine against IBD. For further details, please refer to the publication in journal, Avian Diseases (2016), 60(4):739-751.

Expression of IBDV antigen by splenic dendritic cells obtained from chickens inoculation with IBDV (a) vaccine strain dan (b) very virulent strain. DAPI (blue color) stained the nucleus, FITC-IBDV9 (green color) stained the IBDV VP3 surface protein and  APC-CD86 (red color) stained the spenic dendritic cells surface protein (600x).

Date of Input: 13/06/2017 | Updated: 12/09/2017 | azah