Targeted Delivery Of 5-fluorouracil-1-acetic Acid (5-FA) To Cancer Cells Overexpressing Epithelial Growth Factor Receptor (EGFR) Using Virus-like Nanoparticles | INSTITUTE OF BIOSCIENCE
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Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles

This paper demonstrates the application of hepatitis B virus-like nanoparticle (VLNP) as a specific drug delivery vehicle in the chemotherapy. The VLNP displayed a cell-penetrating peptide that specifically interacts with the epithelial growth factor receptors (EGFR) of cancer cells, and thus enhanced the delivery and efficacy of 5-fluorouracil-1-acetic acid, a newly synthesized anticancer agent, in an EGFR-dependent manner.

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092267789&doi=10.1038%2fs41598-020-73967-4&partnerID=40&md5=75814b66fe7c37a1dfa87bae67302af1

Date of Input: 02/02/2021 | Updated: 02/02/2021 | azah

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