This paper demonstrates the application of hepatitis B virus-like nanoparticle (VLNP) as a specific drug delivery vehicle in the chemotherapy. The VLNP displayed a cell-penetrating peptide that specifically interacts with the epithelial growth factor receptors (EGFR) of cancer cells, and thus enhanced the delivery and efficacy of 5-fluorouracil-1-acetic acid, a newly synthesized anticancer agent, in an EGFR-dependent manner.
Date of Input: 02/02/2021 | Updated: 02/02/2021 | azah
Institute of Bioscience,
Universiti Putra Malaysia,
Email : email@example.com